Connectome psychopharmacology – not for prime time

I attach two article of interest.

The first is predictive descriptive characteristics on connectomes to distinguish depressed patients with suicidality vs depressed patients without suicidality

The Noori article describes the neurochemistry of rat connectome.

I found one article that was a double blind comparison of lithium vs quetiapine in bipolar adolescents.

They found differences between ill and recovered patients but not between drugs, concluding the structural differences were a distal pathway. The best I could tell it was a morphological study so I did not attach it.

A third attached article by Cai et al raises potential serious ethical questions (actualy the ethics is clear,protection from abuse is not)
Connectome data informed which patients had impulsive decision making re money. Great info for sale people.

JT

Joseph (Joe) E. Thornton, M.D., DFAPA
Clinical Associate Professor, Psychiatry
University of Florida College of Medicine
joethornton@ufl.edu

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Noori HR et al 2017 connectome neurochemistry rats.pdf

Cai H et al 2020 Connectomes associated with decisional impulsivity.pdf

Chen VC et al 2021 Suicide and connectomes incl Roger McIntyre.pdf

Tweet by Michelle Cardel, PhD, MS, RD on Twitter

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Michelle Cardel, PhD, MS, RD
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In the nutrition, obesity, and eating disorder (ED) fields, polarizing discourse exists around whether treating obesity and reducing weight stigma and ED psychopathology are mutually exclusive.

Our new publication is out in ⁦‪@eatright‬⁩ journal. A thread of main takeaways: pic.twitter.com/Nl9fsh5F2I

5/31/22, 3:05 PM

Joseph Thornton

Trends in Suicidality 1 Year Before and After Birth Among Commercially Insured Childbearing Individuals in the United States, 2006-2017 | Pregnancy | JAMA Psychiatry | JAMA Network

https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2772882?resultClick=1&utm_source=twitter&utm_medium=social_jn&utm_campaign=article_alert&utm_content=automated_upload

Joseph Thornton

Ethics. Autism. Tweet by Joslyn Chaiprasert-Paguio on Twitter

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Joslyn Chaiprasert-Paguio
⁦‪@JoslynPaguio‬⁩
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PUBLISHED! Second Edition of Practical Ethics for Effective Treatment of Autism Spectrum Disorder. Congratulations ⁦‪@mattbrodhead‬⁩ ⁦‪@davidjcox_‬⁩ & Shawn Quigley. Get your copy TODAY bit.ly/3MKbWCh #bcba #bcaba #aba #apba pic.twitter.com/Jc2k9xzIaG
5/24/22, 11:32 AM

Joseph Thornton

Tweet by Beverly G. Tchang, MD on Twitter

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Beverly G. Tchang, MD
⁦‪@BevTchangMD‬⁩
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Many patients with #diabetes are asking about Mounjaro because they are not tolerating other GLP1s and hoping for the newest #weightloss med. Do we think it will have fewer side effects than Ozempic/Wegovy?

⁦‪@MichaelAlbertMD‬⁩ ⁦‪@DrKarlNadolsky‬⁩ ⁦‪@obsmchat‬⁩ #obsm #endocrine #obesity

5/31/22, 10:25 AM

Joseph Thornton