Just published @NatureMedicine
Randomized trial of tirzepatide (Mounjaro) vs placebo *after* 12 weeks of intensive lifestyle intervention and >5% weight loss nature.com/articles/s4159…
At 72 weeks, Placebo group gained 2.5% weight back; GLP-1 drug lost additional 18.4% body weight pic.twitter.com/dQMswdm0Cz
Large systematic review of over 1,000 trials and 120,000 participants finds that exercise has a significant effect on symptoms of depression, anxiety, and psychological distress.
Cohort study by @andrea_danese and Cathy Widom suggests the link btwn child maltreatment and poor course of emotional disorders is largely attributable to subjective experience of maltreatment, which is partly explained by continuity in psychopathology. ja.ma/3Q2v1nd